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What causes fibromyalgia? All the pieces to solve this scientific puzzle are gathered here.
A centralized source of the most important research and a chain reaction hypothesis tying it all together.
Myofascial Tissue
Contrary to popular belief the muscle in fibromyalgia is NOT normal. Studies have found both structural and functional problems in the myofascial tissue in fibromyalgia. (Myofascial= muscle and its surrounding connective tissue)
1 postImmune System
Fibromyalgia symptoms can be transferred to mice via antibodies from patients, bringing up the question: is it an auto-immune disease? There are also many signs of widespread, but low-grade, inflammation in fibromyalgia.
1 postLatest posts
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Central nervous system key role in abnormal pain processing
This is the most well know aspect of fibromyalgia science, so not as much attention here, but will give summary and links to studies
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Abnormalities in pain-sensing nerves
Position overview paper for peripheral NS dysfunction, small fiber neuropathy
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Fibromyalgia Biomarkers
Overview paper
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Sympathetic (Fight-or-Flight) Nervous system hyperactivity
Position paper
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Sleep problems are the source of many fibromyalgia symptoms
Position paper
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Myofascial abnormalities in fibromyalgia: Position paper
👉This is the missing element to understanding fibromyalgia pain and you aren't going to find this information anywhere else!